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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1J
All Species:
16.67
Human Site:
S218
Identified Species:
33.33
UniProt:
Q5JR12
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JR12
NP_005158.5
505
54834
S218
S
H
L
L
G
P
Q
S
C
W
S
S
Q
K
E
Chimpanzee
Pan troglodytes
XP_513628
505
54871
S218
S
H
L
L
G
P
Q
S
C
W
S
S
Q
K
E
Rhesus Macaque
Macaca mulatta
XP_001096598
450
48605
G203
L
C
L
P
T
T
P
G
T
P
D
S
S
D
P
Dog
Lupus familis
XP_540335
509
54913
S222
S
H
L
V
G
P
Q
S
C
W
S
S
Q
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q149T7
507
55531
S219
S
Q
L
V
S
P
Q
S
C
W
S
P
Q
K
E
Rat
Rattus norvegicus
Q641Y6
504
55192
S217
S
Q
L
V
S
P
Q
S
W
S
P
Q
K
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
M210
R
E
W
R
N
Q
R
M
L
G
G
C
C
A
L
Chicken
Gallus gallus
XP_418000
495
54949
P208
E
V
P
N
D
A
L
P
R
F
H
L
E
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
A243
Q
E
S
L
V
V
G
A
I
E
N
A
F
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608468
651
72868
S214
L
I
I
G
A
L
E
S
A
F
F
N
M
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
K297
S
G
D
Q
R
P
N
K
W
P
F
N
E
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49598
399
43332
K152
G
C
S
H
V
A
E
K
C
R
E
R
L
H
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
93.1
N.A.
88.3
88.3
N.A.
56.1
68.5
N.A.
47.2
N.A.
30.8
N.A.
N.A.
36.1
Protein Similarity:
100
100
86.7
96.2
N.A.
91.3
90.6
N.A.
63.2
77
N.A.
62
N.A.
45
N.A.
N.A.
51.2
P-Site Identity:
100
100
13.3
93.3
N.A.
73.3
33.3
N.A.
0
6.6
N.A.
20
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
13.3
100
N.A.
80
53.3
N.A.
6.6
20
N.A.
40
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
17
0
9
9
0
0
9
0
9
9
% A
% Cys:
0
17
0
0
0
0
0
0
42
0
0
9
9
0
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
9
0
0
17
9
% D
% Glu:
9
17
0
0
0
0
17
0
0
9
9
0
17
9
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
17
0
9
0
0
% F
% Gly:
9
9
0
9
25
0
9
9
0
9
9
0
0
0
0
% G
% His:
0
25
0
9
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
0
0
0
0
9
59
0
% K
% Leu:
17
0
50
25
0
9
9
0
9
0
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
9
0
9
0
0
0
9
17
0
0
0
% N
% Pro:
0
0
9
9
0
50
9
9
0
17
9
9
0
0
9
% P
% Gln:
9
17
0
9
0
9
42
0
0
0
0
9
34
0
0
% Q
% Arg:
9
0
0
9
9
0
9
0
9
9
0
9
0
0
0
% R
% Ser:
50
0
17
0
17
0
0
50
0
9
34
34
9
0
9
% S
% Thr:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% T
% Val:
0
9
0
25
17
9
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
17
34
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _